General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter CHO-K1 GPR150 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0375C2A)
The PathHunter GPR150 (AXOR70) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR150 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR150 and EA-tagged β-Arrestin-2. Activation of GPR150 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Frozen Tissue Array - 37 Different Ovarian Tumors and 3 Corresponding Normal Controls, 5 slides/pk
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's human tumor frozen tissue arrays are designed for studying tumor tissue specific cellular localization of genes or proteins of interest in different human tissues. Same kind of tumors and corresponding normal tissues are mounted on positively charged slides.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Midbrain, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC HS-27A; Bone Marrow; Human (Homo sapiens)
HS-27A is a fibroblast cell line that was isolated in (year from History) from the stroma of a 30-year-old White male donor. This cell line was deposited by B Torok-Storb and can be used in immunology research.
ATCC SK-MEL-3; Malignant Melanoma; Human (Homo sapiens)
SK-MEL-3 is a cell line exhibiting fibroblast morphology that was isolated from the skin of a 42-year-old, White female patient with malignant melanoma. This product has applications in toxicology.
ATCC Genomic RNA from; SARS-CoV-2 Strain:; Germany/BavPat1/2020
Quantitative genomic RNA from Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) strain Germany/BavPat1/2020 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
STEMCELL Technologies Human Whole Peripheral Blood Collected with Sodium Heparin, Fresh, Size: 250 mL
Normal whole peripheral blood (PB) is obtained from healthy donors using Institutional Review Board (IRB)-approved consent forms and protocols. Acid citrate dextrose, solution A (ACDA), Sodium Heparin (Na-Hep), Ethylenediaminetetraacetic acid (EDTA), or Citrate-phosphate-double-dextrose (CP2D) is the anticoagulant.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information and to inquire about donor selection or information including BMI category, smoking status, ethnicity, etc.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Adrenal, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter CHO-K1 CCR4 β-Arrestin Cell Line, 2 vials. (93-0193C2)
The PathHunter CCR4 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL22/MDC) based activation of CCR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR4 and EA-tagged β-Arrestin-2. Activation of CCR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Pseudoalteromonas; luteoviolacea
Pseudoalteromonas luteoviolacea strain CERBOM CH 101 [NCMB 2035] was isolated from seawater near France. This strain is propagated aerobically in marine medium.
Eurofins Discoverx CHO-K1 BRS3 Gq Cell Line, 2 vials. (95-1001C2)
The BRS3 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. bombesin) based activation of BRS3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses BRS3, a naturally Gq coupled GPCR. Upon activation of BRS3, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen APJ Apelin Receptor Membrane Preparation, 1 vial. (HTS068M)
The ChemiScreen APJ Apelin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of AGTRL1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PathHunter U2OS HTR2A β-Arrestin Cell Line, 2 vials. (93-0401C3)
The PathHunter HTR2A cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of HTR2A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2A and EA-tagged β-Arrestin-2. Activation of HTR2A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/human CD47 Stable Cell
Recombinant CHO-K1 cells stably overexpress human CD47 on the surface The surface expression of CD47 on this cell is validated by FACS analysis This cell line is recommended for cell-based binding assay to screening antibodies against CD47 or to measure binding affinity between CD47 and anti-CD47 antibodies